Although proper supplementation can help, depression can really take hold for many. Let’s be mindful of others and reach out when you see someone who may be a little “off”.
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Optimizing NAD levels yields nine crucial benefits for robust health. NAD+ sustains sirtuin enzymes which are vital for health and disease prevention. They also play a major role in depression and anxiety.
Sirtuins are a family of highly conserved NAD+-dependent deacetylases that act as cellular sensors to detect energy availability and modulate metabolic processes.
In a study examining depression, SIRTs were demonstrated to be therapeutic targets for the following reasons:
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SIRTs may control the inflammatory response in depression
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SIRTs might regulate the insufficient level of neurotransmitters in depression
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SIRTs may improve the synaptic dysfunction caused by depression
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Sirtuins may alleviate the cognitive decline caused by depression
Song J and Kim J. Role of Sirtuins in Linking Metabolic Syndrome with Depression. Front. Cell. Neurosci. 10:86. doi: 10.3389/fncel.2016.00086.
Sirtuins are activated by high NAD+ levels and act as intracellular NAD+ sensors. Numerous studies have shown that enhancing NAD+ availability can be used to activate SIRTs and promote beneficial health effects such as the ones cited above.
Integra Nutrition – Longevity Sciences is an award winning brand natural health practitioners have trusted for over 25 years. Our products are Healthy Aging supplement solutions. Numerous studies and 6 years of use by practitioners globally have shown that PRICERA NAD+ Precursor is arguably the best supplement to raise NAD+ levels.